منابع مشابه
Fanconi proteins get histones moving.
FANCD2 is a central player in the DNA damage response, particularly in the repair of spontaneous and chemotherapy-induced DNA interstrand crosslinks. New work by Sato et al (2012a) in The EMBO Journal reveals an unexpected novel function of the FANCD2 protein as a histone chaperone, which appears to be essential for this DNA repair role. Mutation in FANCD2 or 1 of the 14 other FANC genes causes...
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Geographic variation in trees has been investigated since the mid-18th century. Similar patterns of clinal variation have been observed along latitudinal and elevational gradients in common garden experiments for many temperate and boreal species. These studies convinced forest managers that a 'local is best' seed source policy was usually safest for reforestation. In recent decades, experiment...
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ژورنال
عنوان ژورنال: Nature Reviews Neuroscience
سال: 2012
ISSN: 1471-003X,1471-0048
DOI: 10.1038/nrn3389